NSD2-IN-1

CAT: 0931-MF-0052264-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0052264-01Size:25 mg
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CAS Number
2797183-37-8
Target
Others|||Apoptosis
Related Pathways
Apoptosis|||Others
Bioactivity
NSD2-IN-1 (compound 38) is a potent and highly selective inhibitor of NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1), with an IC50 value of 0.11 ?M. By binding to NSD2-PWWP1, NSD2-IN-1 influences gene expression regulated by NSD2, resulting in apoptosis and cell cycle arrest [1].
Smiles
CN1C(=C(N=C1)C2=C(C)C=C(CN3CCC(N)CC3)C=C2C)C=4C5=C(C(C#N)=CC4)C=CC=C5
Molecular Formula
C29H31N5
Molecular Weight
449.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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