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NSD2/H3K36me2 modulator-1

CAT: 0013-GTR19273788-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273788-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSD2/H3K36me2 modulator-1 is an orally active modulator targeting NSD2/H3K36me2. It competitively binds to the SAM pocket of NSD2, effectively inhibiting NSD2 expression and H3K36me2 methylation. This compound can also reverse epithelial-mesenchymal transition (EMT), inhibit cell migration, and induce G0/G1 phase arrest and apoptosis (apoptosis) . Additionally, NSD2/H3K36me2 modulator-1 reduces mitochondrial membrane potential (MMP) and promotes reactive oxygen species (ROS) generation. It is used in research for developing epigenetic anticancer strategies targeting NSD2 in hepatocellular carcinoma (HCC) .
Storage Conditions
-20°C
Notes
For research use only.

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