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Vulolisib

CAT: 0931-T62273-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62273-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2390105-79-8
Target
Others, PI3K
Related Pathways
Others, PI3K/Akt/mTOR signaling
Bioactivity
Vulolisib is an orally active and potent inhibitor of phosphatidylinositol 3 kinase (PI3K), acting on PI3Kα (IC50: 0.2 nM), PI3Kβ (IC50: 168 nM), PI3Kγ (IC50: 90 nM), PI3Kδ (IC50: 49 nM) . activity and exhibits anti-proliferative activity against cancer cells.
Smiles
N([C@H](C(N)=O)C)C=1C=C2C(C=3N(C=C(N3)N4[C@H]([C@H](F)F)CSC4=O)CCO2)=CC1
Molecular Formula
C18H19F2N5O3S
Molecular Weight
423.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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