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Vulolisib

CAT: 0804-HY-147419-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-147419-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vulolisib is a potent and orally active phosphatidylinositol 3-kinase (PI3K) inhibitor, with IC50 values of 0.2 nM, 168 nM, 90 nM and 49 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively. Antiproliferative and antineoplastic activity[1].
CAS Number
2390105-79-8
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vulolisib.html
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC([C@H](C)NC1=CC=C(C2=NC(N3[C@@H](CSC3=O)C(F)F)=CN2CCO4)C4=C1)=O
Molecular Formula
C18H19F2N5O3S
Molecular Weight
423.44
References & Citations
[1]Xiaolan ZHAN, et al. Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof. WO2021104146A1 (example 22)
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

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MBS5804961Vulolisib

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