18-Deoxyherboxidiene

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  18-Deoxyherboxidiene (RQN-18690A) is a potent inhibitor of angiogenesis that selectively acts on SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. It inhibits migration and tube formation in human umbilical vein endothelial cells (HUVEC) without significant cytotoxicity and has potential for cancer research.

• Smiles:

  CCC(OC)C(C)C1OC1(C)CC(C)\C=C\C=C(/C)C1OC(CC(O)=O)CCC1C

• Molecular Formula:

  C25H42O5

• Molecular Weight:

  422.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1200128-66-0