Pan-HER-IN-1

CAT: 0931-T62047-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T62047-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1639040-94-0

Target

EGFR, Apoptosis, Others

Related Pathways

Others, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

Pan-HER-IN-1 (Compound C5) is an irreversible, orally active Pan-HER inhibitor that exhibits IC50 values of 0.38 nM for EGFR, 1.6 nM for HER4, 2.2 nM for EGFR T790M/L858R, and 3.5 nM for HER2, respectively. pan-HER-IN-1 induces apoptosis and demonstrates antitumor activities.

Smiles

N(C=1C2=C(C=CC(NC(C=C)=O)=C2)N=CN1)C=3C=C4C(=CC3)NC=C4Br

Molecular Formula

C19H14BrN5O

Molecular Weight

408.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
MBS5804736	pan-HER-IN-1
BA3217-25	pan-HER-IN-2
MBS1229712-01	Recombinant Caenorhabditis elegans Protein her-1 (her-1)
GTR17963897	Her-1 Antibody
SM-101010-5	Inhibitor of EGFR/HER family (Her1, Her2, Her3 or Pan Her-inhibitor) (BMS-59926/AC480, Mol wt 5671, >99%)
030295	HER-2
HY-163147	PAN endonuclease-IN-1
299230	Rae-1 pan
GTR17964088	Pan-1 Antibody
GTR19234828-01	Pan-HCN-IN-1

Pan-HER-IN-1

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