BNS-22

• Target:

  Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair

• Purity:

  0.9962

• Bioactivity:

  BNS-22 is a DNA topoisomerase II (Topo II) inhibitor with IC?? values of 2.8 ?M and 0.42 ?M for human TopoII? and TopoII?-mediated kinetoplast DNA decatenation, respectively. BNS-22 induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.

• Smiles:

  O=C1OC=2C(=C(OC)C=C(OC)C2C(=C1)CCC)C(=O)N3C=4C=CC=CC4CCC3

• Molecular Formula:

  C24H25NO5

• Molecular Weight:

  407.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1151668-24-4