BNS

• Description:

  BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor[1].

• UNSPSC:

  12352005

• Target:

  HIF/HIF Prolyl-Hydroxylase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bns.html

• Purity:

  96.17

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (CC1=CS/C (N1O) =N\C (CS (=O) (CC2=CC=C3C=CC=CC3=C2) =O) =O) O

• Molecular Formula:

  C18H16N2O6S2

• Molecular Weight:

  420.46

• References & Citations:

  [1]Leung IK, et al. Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors. J Med Chem. 2013 Jan 24;56 (2) :547-55.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1417440-37-9