BNS

• Description :

  BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor[1].

• UNSPSC :

  12352005

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bns.html

• Purity :

  96.17

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(CC1=CS/C(N1O)=N\C(CS(=O)(CC2=CC=C3C=CC=CC3=C2)=O)=O)O

• Molecular Formula :

  C18H16N2O6S2

• Molecular Weight :

  420.46

• References & Citations :

  [1]Leung IK, et al. Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors. J Med Chem. 2013 Jan 24;56 (2) :547-55.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1417440-37-9]