DAPT

• Target:

  Beta Amyloid|||Apoptosis|||Autophagy|||Gamma-secretase

• Related Pathways:

  Neuroscience|||Stem Cells|||Apoptosis|||Autophagy|||Proteases/Proteasome

• Purity:

  0.9981

• Bioactivity:

  DAPT (LY-374973) is a ?-secretase inhibitor that inhibits total A? and A?42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.

• Smiles:

  C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1

• Molecular Formula:

  C23H26F2N2O4

• Molecular Weight:

  432.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  208255-80-5