DAPT

CAT: 0931-MF-0013178-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013178-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
208255-80-5
Target
Beta Amyloid|||Apoptosis|||Autophagy|||Gamma-secretase
Related Pathways
Neuroscience|||Stem Cells|||Apoptosis|||Autophagy|||Proteases/Proteasome
Purity
0.9981
Bioactivity
DAPT (LY-374973) is a ?-secretase inhibitor that inhibits total A? and A?42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.
Smiles
C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1
Molecular Formula
C23H26F2N2O4
Molecular Weight
432.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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