Dovitinib Dilactic Acid

• Target :

  C-Kit|||FLT|||VEGFR|||FGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

• Smiles :

  CC(O)C(O)=O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O

• Molecular Formula :

  C21H21FN6O·2C3H6O3

• Molecular Weight :

  572.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  852433-84-2