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HDAC6-IN-10

CAT: 0931-T61792-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61792-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408286-73-5
Target
HDAC, Others, Microtubule Associated
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Cytoskeletal Signaling, Others
Bioactivity
HDAC6-IN-10 is a potent and specific HDAC6 inhibitor, exhibiting an IC50 value of 0.73 nM. It demonstrates remarkable selectivity towards HDAC6, with a selectivity range of 144 to 10,941-fold over other HDAC isoforms. Furthermore, HDAC6-IN-10 exhibits notable anti-proliferative effects on multiple myeloma cells [1].
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N(CC4=CC=C(C(NO)=O)C=C4)CC(=O)N3
Molecular Formula
C21H20N4O4
Molecular Weight
392.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C