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PARP1-IN-10

CAT: 0931-T61694-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61694-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2494001-21-5
Target
Others, PARP, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis, Others, DNA Damage/DNA Repair
Bioactivity
PARP1-IN-10 (compound 12c) is a highly potent and non-cytotoxic PARP1 inhibitor with an in vitro IC50 value of 50.62 nM, effectively inducing cell cycle arrest at the G2/M phase and apoptosis, while significantly augmenting the cytotoxic effects of temozolomide (TMZ) [1].
Smiles
C(=C1C(=O)N(C)C(=O)N(C)C1=O)C2=CC=C(OCC(=O)N3CCCCC3)C=C2
Molecular Formula
C20H23N3O5
Molecular Weight
385.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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