Rucaparib acetate

• Target:

  Others|||PARP

• Related Pathways:

  Others|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Bioactivity:

  Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC) . [1] [2] [3] [4]

• Smiles:

  CC(O)=O.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

• Molecular Formula:

  C21H22FN3O3

• Molecular Weight:

  383.423

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  773059-23-7