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Rucaparib acetate

CAT: 0931-T61657-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61657-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
773059-23-7
Target
Others, PARP
Related Pathways
Others, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC) . [1] [2] [3] [4]
Smiles
CC(O)=O.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Molecular Formula
C21H22FN3O3
Molecular Weight
383.423
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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