Rucaparib

• Target :

  PARP

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity :

  0.9989

• Bioactivity :

  Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC) .

• Smiles :

  O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

• Molecular Formula :

  C19H18FN3O

• Molecular Weight :

  323.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  283173-50-2