Rucaparib

• Target:

  PARP

• Related Pathways:

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity:

  0.9989

• Bioactivity:

  Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC) .

• Smiles:

  O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

• Molecular Formula:

  C19H18FN3O

• Molecular Weight:

  323.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  283173-50-2