THK-5105

• Target :

  Others|||Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Bioactivity :

  THK-5105, an arylquinoline derivative, demonstrates high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicating its potential as a tau imaging PET (Positron Emission Tomography) probe with the radiolabeled version, 18F-THK-5105 [1].

• Smiles :

  O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(N(C)C)C=C3)C=C1

• Molecular Formula :

  C20H21FN2O2

• Molecular Weight :

  340.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1374107-46-6