Fenspiride

• CAS Number :

  1151767

• Target :

  Others|||PDE|||Histamine Receptor

• Related Pathways :

  Immunology/Inflammation|||Metabolism|||GPCR/G Protein|||Neuroscience|||Others

• Bioactivity :

  Fenspiride is an antagonist of H1-histamine receptors. Fenspiride is an orally active non-steroidal anti-inflammatory agent that can be used for the treatment of respiratory tract infections and otitis media. Fenspiride inhibited phosphodiesterase 4 and phosphodiesterase 3 activities with -logIC50 values of 4.16+/-0.09 and 3.44+/-0.12, respectively. Phosphodiesterase 5 activity was also inhibited with a -logIC50 value of approximately 3.8.

• Smiles :

  O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1

• Molecular Formula :

  C15H20N2O2

• Molecular Weight :

  260.33

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C