DHFR-IN-2

• Target:

  Others|||Antifolate

• Related Pathways:

  Others|||Cell Cycle/Checkpoint

• Bioactivity:

  DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 ?M. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].

• Smiles:

  C(NC1=CC=CC=C1)C2=CC(C(O)=O)=CC=C2

• Molecular Formula:

  C14H13NO2

• Molecular Weight:

  227.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  331942-46-2