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DHFR-IN-2

CAT: 0931-T60286-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T60286-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
331942-46-2
Target
Others|||Antifolate
Related Pathways
Others|||Cell Cycle/Checkpoint
Bioactivity
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 ?M. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].
Smiles
C(NC1=CC=CC=C1)C2=CC(C(O)=O)=CC=C2
Molecular Formula
C14H13NO2
Molecular Weight
227.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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