Products for Research Use Only
RegisterLogin

PBRM1-BD2-IN-5

CAT: 0931-T60159-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T60159-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2819989-61-0
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9955
Bioactivity
PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, with dissociation constant (Kd) values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5 respectively, and an inhibitory concentration 50 (IC50) value of 0.26 μM for PBRM1-BD2. This compound effectively diminishes the interaction between full-length PBRM1 and acetylated histone peptide within the PBAF complex in cell lysates, making it a promising candidate for anticancer research.
Smiles
O=C1C=2C(NC(N1)C3=CC(C)=CC=C3)=CC=CC2Cl
Molecular Formula
C15H13ClN2O
Molecular Weight
272.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T60155-01PBRM1-BD2-IN-7
T60156-01PBRM1-BD2-IN-2
T72843-01PBRM1-BD2-IN-6
T72841-01PBRM1-BD2-IN-1
T60158-01PBRM1-BD2-IN-3
T60157-01PBRM1-BD2-IN-8
T79527-01BET BD2-IN-1
T206487-01Pan-BET/BD2-IN-1
T207244-01PBRM1/SMARCA2,4 binder-1
T207299-01PBRM1/SMARCA2,4-ligand-1

Alternative Products

CatalogName
BA4703-50PBRM1-BD2-IN-5
BA4714-5PBRM1-BD2-IN-8
BUP08962-01PBRM1-BD2-IN-3
GTR19212946-01PBRM1-BD2-IN-6
MBS5802920PBRM1-BD2-IN-2
M35348-01PBRM1-BD2-IN-7
HY-151528PBRM1-BD2-IN-1

Popular Products