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BV02

CAT: 0931-T60081-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T60081-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
292870-53-2
Target
Autophagy, Akt, Apoptosis, Caspase, PARP, Others, Antibacterial, Bcr-Abl
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic, Autophagy, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Angiogenesis, Others, Proteases/Proteasome, Microbiology/Virology, Cytoskeletal Signaling
Purity
0.9982
Bioactivity
BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
Smiles
Cc1c(N2C(=O)c3ccc(cc3C2=O)C(O)=O)c(=O)n(-c2ccccc2)n1C
Molecular Formula
C20H15N3O5
Molecular Weight
377.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid

BV02 is an organic molecular entity.

CAS Number292870-53-2
PubChem CID1087337
IUPAC Name2-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,3-dioxoisoindole-5-carboxylic acid
Molecular FormulaC20H15N3O5
Molecular Weight377.3
XLogP2.3
Topological Polar Surface Area98.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity770
SMILES
CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N3C(=O)C4=C(C3=O)C=C(C=C4)C(=O)O
InChI
InChI=1S/C20H15N3O5/c1-11-16(19(26)23(21(11)2)13-6-4-3-5-7-13)22-17(24)14-9-8-12(20(27)28)10-15(14)18(22)25/h3-10H,1-2H3,(H,27,28)
InChIKey
ZFYSDSINNOLWGO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid
CAS: 292870-53-2
CID: 1087337
Formula: C20H15N3O5
MW: 377.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight377.3
XLogP32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass377.10117059
Monoisotopic Mass377.10117059
Topological Polar Surface Area98.2 Ų
Heavy Atom Count28
Formal Charge0
Complexity770
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
565260BV02

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