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BV02

CAT: 0013-GTR19171853-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171853-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BV02 is a small molecule inhibitor of 14-3-3 protein-protein interactions. It is used in chronic myeloid leukemia research to disrupt cells harboring both wild-type and therapy-resistant T315I Bcr-Abl mutations, as demonstrated in various cellular studies.
CAS Number
292870-53-2
Product Name Alternative
14-3-3 protein-protein interaction, 2- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) -1,3-dioxoisoindoline-5-carboxylic acid, BV 02, BV02, BV-02
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction
Purity
99.79% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.5 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.65 mM)
Smiles
Cc1c (N2C (=O) c3ccc (cc3C2=O) C (O) =O) c (=O) n (-c2ccccc2) n1C
Molecular Formula
C20H15N3O5
Molecular Weight
377.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid

BV02 is an organic molecular entity.

CAS Number292870-53-2
PubChem CID1087337
IUPAC Name2-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,3-dioxoisoindole-5-carboxylic acid
Molecular FormulaC20H15N3O5
Molecular Weight377.3
XLogP2.3
Topological Polar Surface Area98.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity770
SMILES
CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N3C(=O)C4=C(C3=O)C=C(C=C4)C(=O)O
InChI
InChI=1S/C20H15N3O5/c1-11-16(19(26)23(21(11)2)13-6-4-3-5-7-13)22-17(24)14-9-8-12(20(27)28)10-15(14)18(22)25/h3-10H,1-2H3,(H,27,28)
InChIKey
ZFYSDSINNOLWGO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid
CAS: 292870-53-2
CID: 1087337
Formula: C20H15N3O5
MW: 377.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight377.3
XLogP32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass377.10117059
Monoisotopic Mass377.10117059
Topological Polar Surface Area98.2 Ų
Heavy Atom Count28
Formal Charge0
Complexity770
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8802-5.1BV02

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