Indinavir

• Target:

  SARS-CoV|||MMP|||Apoptosis|||HIV Protease

• Related Pathways:

  Microbiology/Virology|||Apoptosis|||Proteases/Proteasome

• Bioactivity:

  Indinavir is an orally administered, specific HIV protease inhibitor commonly used in combination therapy as part of highly active antiretroviral therapy (HAART) for HIV/AIDS. Indinavir also inhibits the activation of MMP-2 in endothelial cells and exhibits affinity for ?7-nAchR and SARS-CoV-2 Mpro.

• Smiles:

  N(C([C@H](CC1=CC=CC=C1)C[C@@H](CN2[C@H](C(NC(C)(C)C)=O)CN(CC=3C=CC=NC3)CC2)O)=O)[C@H]4C=5C(C[C@H]4O)=CC=CC5

• Molecular Formula:

  C36H47N5O4

• Molecular Weight:

  613.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  150378-17-9