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CAFESTOL

CAT: 0931-T5727-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T5727-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
469-83-0
Target
ERK, FAK, Autophagy, COX, NF-κB, Apoptosis, DNA/RNA Synthesis, PGE Synthase
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, Autophagy, Cytoskeletal Signaling, Neuroscience, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, MAPK, Immunology/Inflammation, NF-κB
Purity
0.9984
Bioactivity
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX) -2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.
Smiles
[H][C@@]12C[C@]3(C[C@]1(O)CO)CC[C@]1([H])c4ccoc4CC[C@@]1(C)[C@]3([H])CC2
Molecular Formula
C20H28O3
Molecular Weight
316.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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