CAFESTOL

• Target:

  ERK|||FAK|||Autophagy|||COX|||NF-?B|||Apoptosis|||DNA/RNA Synthesis|||PGE Synthase

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||Apoptosis|||Autophagy|||Cytoskeletal Signaling|||Neuroscience|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||MAPK|||Immunology/Inflammation|||NF-?B

• Purity:

  0.9984

• Bioactivity:

  CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX) -2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.

• Smiles:

  [H][C@@]12C[C@]3(C[C@]1(O)CO)CC[C@]1([H])c4ccoc4CC[C@@]1(C)[C@]3([H])CC2

• Molecular Formula:

  C20H28O3

• Molecular Weight:

  316.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  469-83-0