ML 297

• Target:

  Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  0.9785

• Bioactivity:

  ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively) . ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.

• Smiles:

  Cc1cc (NC (=O) Nc2ccc (F) c (F) c2) n (n1) -c1ccccc1

• Molecular Formula:

  C17H14F2N4O

• Molecular Weight:

  328.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1443246-62-5