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Tropifexor

CAT: 0931-T4379-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4379-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1383816-29-2
Target
FXR, Autophagy
Related Pathways
Autophagy, Metabolism
Purity
0.9985
Bioactivity
Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.
Smiles
OC(=O)c1cc(F)c2nc(sc2c1)N1[C@H]2CC[C@@H]1C[C@@H](C2)OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1
Molecular Formula
C29H25F4N3O5S
Molecular Weight
603.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C