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AY 77

CAT: 0931-T41190-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T41190-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1835734-92-3
Target
Protease-activated Receptor|||ERK|||Calcium Channel
Related Pathways
Metabolism|||GPCR/G Protein|||MAPK|||Membrane transporter/Ion channel
Purity
0.997
Bioactivity
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 ?M) . AY 77 can promote migration of human breast cancer cells in vitro.
Smiles
[C@H](CC1CCCCC1)(C(N[C@H](C(N)=O)[C@@H]2CCCCC2)=O)NC(=O)C3=CC=NO3
Molecular Formula
C21H32N4O4
Molecular Weight
404.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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