AY 77

• Target:

  Protease-activated Receptor|||ERK|||Calcium Channel

• Related Pathways:

  Metabolism|||GPCR/G Protein|||MAPK|||Membrane transporter/Ion channel

• Purity:

  0.997

• Bioactivity:

  AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 ?M) . AY 77 can promote migration of human breast cancer cells in vitro.

• Smiles:

  [C@H](CC1CCCCC1)(C(N[C@H](C(N)=O)[C@@H]2CCCCC2)=O)NC(=O)C3=CC=NO3

• Molecular Formula:

  C21H32N4O4

• Molecular Weight:

  404.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1835734-92-3