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OB 24 hydrochloride

CAT: 0931-T41175Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T41175Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
939825-12-4
Target
ROS, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA) . Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
Smiles
Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
Molecular Formula
C15H18BrClN2O2
Molecular Weight
373.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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