JTS-653

• Target :

  Others|||TRP/TRPV Channel

• Related Pathways :

  Others|||Membrane transporter/Ion channel

• Bioactivity :

  JTS-653 is a potent and selective in vitro and in vivo antagonist of transient receptor potential vanilloid 1 (TRPV1) . It effectively attenuates chronic pain resistant to non-steroidal anti-inflammatory drugs.

• Smiles :

  Cc1ccc(nc1)N1[C@@H](CO)COc2c1cccc2C(=O)Nc1ccc(OCC(F)(F)F)nc1

• Molecular Formula :

  C23H21F3N4O4

• Molecular Weight :

  474.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  942614-99-5