JTS-653

• Target:

  Others|||TRP/TRPV Channel

• Related Pathways:

  Others|||Membrane transporter/Ion channel

• Bioactivity:

  JTS-653 is a potent and selective in vitro and in vivo antagonist of transient receptor potential vanilloid 1 (TRPV1) . It effectively attenuates chronic pain resistant to non-steroidal anti-inflammatory drugs.

• Smiles:

  Cc1ccc(nc1)N1[C@@H](CO)COc2c1cccc2C(=O)Nc1ccc(OCC(F)(F)F)nc1

• Molecular Formula:

  C23H21F3N4O4

• Molecular Weight:

  474.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  942614-99-5