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5-Hydroxymethyl-2'-deoxycytidine

CAT: 0931-T40834-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T40834-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
7226-77-9
Target
DNA/RNA Synthesis, PARP
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9995
Bioactivity
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine in DNA. Hydroxymethyl-2'-deoxycytidine replication fork instability is associated with the presence of poly (ADP-ribose) polymerase 1 (PARP1) on chromatin.
Smiles
Nc1nc(=O)n(cc1CO)[C@H]1C[C@H](O)[C@@H](CO)O1
Molecular Formula
C10H15N3O5
Molecular Weight
257.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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