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CCR4 antagonist 3

CAT: 0931-T39661Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T39661Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2174938-70-4
Target
CCR, Others
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others, Microbiology/Virology
Bioactivity
CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.
Smiles
[H][C@@]1(CCCN(CCO)C1)C1CN(C1)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N
Molecular Formula
C24H27Cl2N7O
Molecular Weight
500.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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