ABM-14

• Target:

  Others|||Ligands for Target Protein for PROTAC

• Related Pathways:

  Others|||PROTAC

• Bioactivity:

  ABM-14, a ligand for the androgen receptor (AR), is utilized as a targeting agent in PROTAC. By binding to a ligand for the von Hippel-Lindau protein (VHL) via a linker, ABM-14 forms ARCC-4, which facilitates the degradation of AR.

• Smiles:

  CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc(O)cc1

• Molecular Formula:

  C25H18F3N3O2S

• Molecular Weight:

  481.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1973408-76-2