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MLK-IN-1

CAT: 0931-T39102-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39102-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1627729-62-7
Target
MLK
Related Pathways
MAPK
Purity
0.9974
Bioactivity
MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.
Smiles
N=1C=C(C=2SC=3C(OC)=CC=CC3C2)N4N=C(C=CC14)NC5=CC=C(OC)C(OC)=C5
Molecular Formula
C23H20N4O3S
Molecular Weight
432.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA6508-10MLK-IN-1
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Pab-605004MLK-3
HY-161271-01MLK-IN-2
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323103MAP3K11 (Mitogen-activated protein kinase kinase kinase 11, MLK3, PTK1, SPRK, MLK-3, MEKK11) discontinued
500273MLK3, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 3, MAP3K11, PTK1, SPRK, MLK3, MGC17114, MLK-3) discontinued
223975-01LZK (Mitogen-Activated Protein Kinase Kinase Kinase 13, Leucine Zipper-bearing Kinase, Mixed lineage Kinase, MLK, MAP3K13, LZK) discontinued
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