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ALK-IN-12

CAT: 0931-T38584Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T38584Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1197958-53-4
Target
Others, ALK
Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
ALK-IN-12 is a highly potent and orally active inhibitor of anaplastic lymphoma kinase (ALK), demonstrating an exceptional IC50 value of 0.18 nM. Additionally, ALK-IN-12 displays inhibitory activity against insulin-like growth factor 1 receptor (IGF1R) and insulin receptor (InsR), with IC50 values of 20.3 nM and 90.6 nM, respectively. Notably, its antitumor effects have been observed, making it a promising compound for targeted cancer therapy.
Smiles
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1)N1CCN(C)CC1
Molecular Formula
C24H30ClN6O2P
Molecular Weight
500.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
MBS5799211ALK-IN-12
sc-398791ALK (F-12)
sc-398791 FITCALK (F-12) FITC
sc-398791 PEALK (F-12) PE
sc-398791 HRPALK (F-12) HRP
sc-398791 PALK (F-12) P
sc-398791 ACALK (F-12) AC
sc-398791 AF488ALK (F-12) Alexa Fluor® 488
sc-398791 AF680ALK (F-12) Alexa Fluor® 680
sc-398791 AF594ALK (F-12) Alexa Fluor® 594

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