RTIL 13

CAT: 0931-T38407Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T38407Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1009376-10-6

Target

Others, Ras

Related Pathways

MAPK, GPCR/G Protein, Others

Bioactivity

RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.

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[Br-].[H][C@]12CC[C@]([H])(O1)[C@]1([H])C(=O)N(CC[N+](C)(C)CCCCCCCCCCCCCCCCCC)C(=O)[C@]21[H] |THB:36:38:7:3.4,10:8:7:3.4|

Molecular Formula

C30H55BrN2O3

Molecular Weight

571.685

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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