RTIL 13

CAT: 0931-MF-0152554Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0152554Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1009376-10-6
Target
Others|||Ras
Related Pathways
MAPK|||GPCR/G Protein|||Others
Bioactivity
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 ?M for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 ?M and 7.1 ?M, respectively.
Smiles
[Br-].[H][C@]12CC[C@]([H])(O1)[C@]1([H])C(=O)N(CC[N+](C)(C)CCCCCCCCCCCCCCCCCC)C(=O)[C@]21[H]|THB:36:38:7:3.4,10:8:7:3.4|
Molecular Formula
C30H55BrN2O3
Molecular Weight
571.685
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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