11-cis Retinol

CAT: 0931-T38220Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T38220Size:1 mg

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CAS Number

22737-96-8

Target

Others, Endogenous Metabolite

Related Pathways

Metabolism, Others

Bioactivity

11-cisRetinol is an isomer of vitamin A . It is formed from vitamin A, viaatrans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle.1,211-cisRetinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells.3It promotes pigment formation in cone, but not rod, photoreceptors.

Smiles

C\C(=C/CO)\C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C |c:12|

Molecular Formula

C20H30O

Molecular Weight

286.459

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

11-cis-Retinol

11-cis-retinol is a retinol. It has a role as a mouse metabolite and a human metabolite.

CAS Number	22737-96-8
PubChem CID	5280382
IUPAC Name	(2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
Molecular Formula	C20H30O
Molecular Weight	286.5
XLogP	5.7
Topological Polar Surface Area	20.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Heavy Atom Count	21
Formal Charge	0
Complexity	496

SMILES

CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C\C(=C\CO)\C)/C

InChI

InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6-,12-11+,16-8+,17-13+

InChIKey

FPIPGXGPPPQFEQ-IOUUIBBYSA-N

Chemical Structure

2D Structure

CAS: 22737-96-8

CID: 5280382

Formula: C20H30O

MW: 286.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	286.5
XLogP3	5.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Exact Mass	286.229665576
Monoisotopic Mass	286.229665576
Topological Polar Surface Area	20.2 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	496
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	4
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T38219	11-cis Retinal
TYD-00699-01	Cis-11-Hexadecenal
TCL-00072-01	Methyl cis-11-octadecenoate
T10038-01	11-cis-Vaccenyl acetate
TYD-02938-01	3-Oxoeicosa-cis, cis-11,14-dienoyl-CoA
TYD-04253-01	Trans, cis, cis-2,11,14-Eicosatrienoyl-CoA
TYD-04090-01	Cis-11,12-Methyleneoctadecanoyl-CoA
TYD-02261-01	(3S) -Hydroxy-eicosa-cis, cis-11,14-dienoyl-CoA
T74029-01	Cis-11-Methyl-2-dodecenoic acid
T19169	9-cis-Retinal

Alternative Products

Catalog	Name
FR163659-01	11-cis-Retinol
MBS5798932	11-cis Retinol
TRC-R252105-10MG	11-cis-Retinol, >85%
490317	RDH11 (Retinol Dehydrogenase 11, Retinol Dehydrogenase 11 (All-Trans/9-cis/11-cis) )
R1702-21A	RDH5 (11-cis Retinol Dehydrogenase, 11-cis RDH, RDH1)
332474	Retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
490323	RDH5 (11-cis Retinol Dehydrogenase, Retinol Dehydrogenase 5)
272289-01	11-cis-13,14-Dihydro retinol
abx006603-01	11-Cis Retinol Dehydrogenase (RDH5) Antibody
abx616268	11-Cis Retinol Dehydrogenase (RDH5) Peptide

11-cis Retinol

Chemical Information

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