11-cis Retinal

• Target :

  Others|||Endogenous Metabolite

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.

• Smiles :

  C/C(/C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C\C=O|c:9|

• Molecular Formula :

  C20H28O

• Molecular Weight :

  284.443

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  564-87-4