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Ac-LEHD-AMC

CAT: 0931-T36342-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36342-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
292633-16-0
Target
Caspase, Others
Related Pathways
Apoptosis, Others, Proteases/Proteasome
Bioactivity
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Smiles
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Molecular Formula
C33H41N7O11
Molecular Weight
711.729
Shipping Conditions
Ice Packs
Storage Temperature
-20°C