NS 6740

CAT: 0931-T37390Size: 50 mgDry Ice: NoHazardous: No

CAT#:0931-T37390Size:50 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

753499-14-8

Target

Others

Related Pathways

Others

Bioactivity

High affinity ?7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human) . Inhibits ACh (IC50 = 2.7 nM) at ?7 nAChR. Reduces LPS-induced TNF-? release from microglia enriched cultures. Anti-inflammatory.

Smiles

Cl.FC(F)(F)c1cccc(c1)-c1ccc(o1)C(=O)N1CCN2CCC1CC2|TLB:16:18:22.23:25.26|

Molecular Formula

C19H20ClF3N2O2

Molecular Weight

400.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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