PCTR1

CAT: 0931-T37300-01Size: 10 µgDry Ice: NoHazardous: No
CAT#:0931-T37300-01Size:10 µg
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CAS Number
1810710-59-8
Target
Others|||Antibacterial
Related Pathways
Others|||Microbiology/Virology
Bioactivity
Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.
Smiles
[C@@H](CS[C@H](/C=C/C=C/C=C\C/C=C\C/C=C\CCC(O)=O)[C@H](C/C=C\CC)O)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O
Molecular Formula
C32H47N3O9S
Molecular Weight
649.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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CatalogName
T37301-01PCTR2
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Alternative Products

CatalogName
MBS5798236PCTR1
208064CDKN2A (Arf, ARF-INK4a, CDK4I, Cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), Cyclin-dependent kinase inhibitor 2A isoforms 1/2, Cyclin-dependent kinase inhibitor protein, Ink4a/Arf, INK4a-ARF, Mitochondrial smARF, MTS1, OTTMUSP00000008143, p16, p16 (INK4a), p16-INK4, p16INK4a, p16-INK4a, p19ARF, Pctr1, RP23-166I8.5)

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