Products for Research Use Only
RegisterLogin

CAY10787

CAT: 0931-T37201-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T37201-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
567-72-6
Target
GABA Receptor, Others
Related Pathways
Neuroscience, Others, Membrane transporter/Ion channel
Bioactivity
CAY10787 is an oxysterol and a negative allosteric modulator of GABAAreceptors.1,2It reduces GABA-induced currents in HEK cells expressing α1β1γ2or α4β3γ2subunit-containing GABAAreceptors (IC50s = 1.5 and 1 μM, respectively) .2CAY10787 (500 nM) reduces GABA-induced depolarization of peptidergic and non-peptidergic nociceptors, C-LTMRs, and cold thermosensors in isolated mouse dorsal root ganglion (DRG) neurons.
Smiles
[H][C@@]1(CC[C@@]2([H])[C@]3([H])C(=O)C=C4C=CCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C |c:12,t:10|
Molecular Formula
C27H42O
Molecular Weight
382.632
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T37424-01CAY10781
T37833-01CAY10767
T36393-01CAY10727
T36035-01CAY10784
T36036-01CAY10786
T35985-01CAY10487
T71273-01CAY10788
T60439-01CAY10789
T36197-01CAY10747
T36463-01CAY10777

Alternative Products

CatalogName
MBS5798150CAY10787

Popular Products