Resolvin D1 methyl ester

CAT: 0931-T37168-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0931-T37168-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

937738-63-1

Target

Others

Related Pathways

Others

Bioactivity

Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

Smiles

[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CC)O)O)(C/C=C\CCC(OC)=O)O

Molecular Formula

C23H34O5

Molecular Weight

390.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Resolvin D1 methyl ester

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