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Boc-LRR-AMC

CAT: 0931-T37011-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T37011-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
109358-46-5
Target
Others
Related Pathways
Others
Bioactivity
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Smiles
CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Molecular Formula
C33H52N10O7
Molecular Weight
700.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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