SM1-71

• Target :

  FGFR|||LIM Kinase|||Serine/threonin kinase|||MAPK|||TGF-beta/Smad|||Src|||S6 Kinase|||AAK1

• Related Pathways :

  Neuroscience|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Angiogenesis|||MAPK|||Metabolism|||Stem Cells

• Purity :

  0.96

• Bioactivity :

  SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines.

• Smiles :

  CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1

• Molecular Formula :

  C24H26ClN7O

• Molecular Weight :

  463.96

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2088179-99-9