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Dehydro Nifedipine

CAT: 0931-T36665-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36665-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
67035-22-7
Target
Drug Metabolite
Related Pathways
Metabolism
Purity
0.9951
Bioactivity
Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
Smiles
COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+]([O-])=O
Molecular Formula
C17H16N2O6
Molecular Weight
344.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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