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Nifedipine

CAT: 0931-T1146-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0931-T1146-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
21829-25-4
Target
Calcium Channel, CaMK, Potassium Channel, Autophagy
Related Pathways
Autophagy, Membrane transporter/Ion channel, Metabolism, Neuroscience
Purity
0.9949
Bioactivity
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.
Smiles
COC(=O)C1=C(C)NC(C)=C(C1C1=C(C=CC=C1)[N+]([O-])=O)C(=O)OC
Molecular Formula
C17H18N2O6
Molecular Weight
346.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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