BMS-1

• Target:

  PD-1/PD-L1|||Apoptosis

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation

• Purity:

  0.9986

• Bioactivity:

  BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

• Smiles:

  COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O

• Molecular Formula:

  C29H33NO5

• Molecular Weight:

  475.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1675201-83-8