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CAY10770

CAT: 0931-T36462-01Size: 250 µgDry Ice: NoHazardous: No
CAT#:0931-T36462-01Size:250 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2428734-45-4
Target
Cytochromes P450|||Others
Related Pathways
Metabolism|||Others
Bioactivity
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 ?M) .1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 ?M) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 ?M, respectively) . CAY10770 (3 ?M) inhibits the production of 14 (15) -EET, 19-HETE, and 14 (15) -DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.
Smiles
N(CCCCCCCC(O)=O)N1C=2C(N=N1)=CC=CC2
Molecular Formula
C14H20N4O2
Molecular Weight
276.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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