SJF 1521

• Target:

  EGFR|||PROTACs

• Related Pathways:

  JAK/STAT signaling|||PROTAC|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.992

• Bioactivity:

  SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.

• Smiles:

  N (C=1C2=C (C=CC (=C2) C3=CC=C (OCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (O) C4) [C@] (C) (C) C) =O) C=C3) N=CN1) C7=CC (Cl) =C (OCC8=CC (F) =CC=C8) C=C7

• Molecular Formula:

  C57H61ClFN7O9S

• Molecular Weight:

  1074.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2230821-40-4