SJF?

• CAS Number :

  2254609-23-7

• Target :

  Others|||p38 MAPK|||PROTACs|||Autophagy

• Related Pathways :

  PROTAC|||Others|||Autophagy|||MAPK

• Bioactivity :

  SJF? is a 10-atom linker PROTAC that selectively degrades p38? with a DC50 of 46.17 nM, without degrading p38?, p38?, or p38?[1].

• Smiles :

  C(NC1=CC(F)=C(OC=2C3=C(C=C(OCCOCCOCCOC4=C(CNC(=O)[C@H]5N(C([C@H](C(C)C)N6CC=7C(C6=O)=CC=CC7)=O)C[C@H](O)C5)C=CC(=C4)C=8SC=NC8C)C(OC)=C3)N=CC2)C=C1)(=O)C9(C(NC%10=CC=C(F)C=C%10)=O)CC9

• Molecular Formula :

  C62H63F2N7O12S

• Molecular Weight :

  1168.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C