GSM III

• Target :

  Gamma-secretase|||Beta Amyloid

• Related Pathways :

  Proteases/Proteasome|||Stem Cells|||Neuroscience

• Bioactivity :

  GSM III is a modulator of the ?-secretase complex (GSEC) . It significantly influences the length of amyloid ? protein (A?) at the extracellular interface between the protease components (NCT, PSEN) and the substrate APPC99. GSM III is applied in Alzheimer's disease (AD) research.

• Smiles :

  C(C=1C=2C(N(C)C1)=CC=C(C(F)(F)F)C2)N3C(=O)C=4N(C[C@H]3C)C(=O)C(=CC4)N5C=NC(C)=C5

• Molecular Formula :

  C24H22F3N5O2

• Molecular Weight :

  469.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1493797-28-6