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GSM III

CAT: 0931-T211685-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211685-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1493797-28-6
Target
Gamma-secretase|||Beta Amyloid
Related Pathways
Proteases/Proteasome|||Stem Cells|||Neuroscience
Bioactivity
GSM III is a modulator of the ?-secretase complex (GSEC) . It significantly influences the length of amyloid ? protein (A?) at the extracellular interface between the protease components (NCT, PSEN) and the substrate APPC99. GSM III is applied in Alzheimer's disease (AD) research.
Smiles
C(C=1C=2C(N(C)C1)=CC=C(C(F)(F)F)C2)N3C(=O)C=4N(C[C@H]3C)C(=O)C(=CC4)N5C=NC(C)=C5
Molecular Formula
C24H22F3N5O2
Molecular Weight
469.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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